Introduction of Actemra Injection

• Actemra 400 mg Injection is oral and small molecule medicine belongs to JAK inhibitors used for the treatment of Rheumatoid Arthritis in adults who were not responded well with other RA medications. It is also approved treatment for Psoriatic Arthritis and Ulcerative Colitis due to it's immunosuppressant property. It should not be use with other biologics or immunosuppressants. It is long term treatment so continue it on regular basis even if you don't find any visible relief in your condition. Do not double your dose even on you missed the scheduled dose. Actemra 400 mg Injection can not be started if, Rheumatoid arthritis is not active or you haven't tried other treatment options available for such condition. One should avoid taking Actemra 400 mg Injection if patient is lactose intolerant. Safety is not established in pregnant women and lactating mother. Inform your health care provider if other medical conditions co-exist like renal impairment, hepatic impairment, recurrent infections, or other vascular disorders.

Uses of Actemra Injection

• • Moderate to severe Rheumatoid Arthritis
  • Active Psoriatic arthritis
  • Ulcerative Colitis and other Inflammatory Bowel disease
  • Juvenile Idiopathic Arthritis in Children more than 2 years of age.

Benefits of Actemra Injection

• Actemra 400 mg Injection provides relief in pain, swelling and joint tenderness resulted from rheumatoid arthritis and psoriatic arthritis. Actemra 400 mg Injection also gives response in patients who doesn't responded well with other Disease-modifying antirheumatic drugs (DMARDs)

Side Effects of Actemra Injection

Most Common Side Effects of Actemra Injection

• • Diarrhoea
  • Headache
  • Throat, Nasal and Chest infections
  • Skin infections
  • Tiredness
  • Yellow Eyes and Skin.
  • Appetite loss
  • Vomiting
  • Darker Urine and Tarry stool
  • skin rashes
  • Short breathing
  • Chest pain
  • Coughing and Sneezing with blood and Mucus
  • redness and Swelling of Skin
  • painful Urination
  • Weigh loss
  • Changes in Frequency and Consistency of passing stool.

Common Side Effects of Actemra Injection

• • Blood Clots
  • sudden shortness of Breath
  • Painful Breathing
  • Chest Pain
  • Heavy Sweating
  • Redness, Painful and Swollen limbs.

How to Use Actemra Injection?

• Actemra 400 mg Injection is taken Orally with or without food. Usually taken two tablets a day or as per your doctor's consultation.

How Actemra Injection Works?

• Actemra 400 mg Injection primarily inhibits the Janus Kinase(JAK) Enzymes which are group of Intracellular Enzymes responsible for Immune Cell function. Therapeutically it blocks JAK-STAT pathway to minimize the inflammatory response that ultimately leads to immunosuppression.