Materna Depot 3.75 mg Injection injection is a Synthetically prepared Nonapeptide having Potent gonadotropin-releasing hormone receptor (GnRHR) agonist activity. Generally, it is used different Clinical Conditions, including Uterine Fibroids, Prostate cancer, Endometriosis, and in vitro fertilization techniques. Materna Depot 3.75 mg Injection has proven efficacy in the treatment of Central Precocious Puberty in children.

• Advanced Prostate cancer
• Endometriosis
• Uterine Leiomyomata (Fibroids)
• Breast Cancer in Premenopausal Ovarian Ablation
• Central Precocious puberty
• In vitro fertilization
• Transgender Hormone therapy

Materna Depot 3.75 mg Injection injection is available as depot suspension, which gets deposited in fatty tissues for a longer period leads to sustained action. Materna Depot 3.75 mg Injection is given IM or Subcutaneously, so less painful compared to the other administration route.

• Constipation
• Weight Fluctuation
• Muscle pain
• Runny nose
• Abdominal Pain
• Acne
• Nervousness
• Difficulty in remembering things
• Spotting
• Irregular menstruation
• Vaginal discharge
• Decreased Sexual Desire
• Change in Breast Size
• Hot flashes
• Intense sweating
• Tingling sensation on feet and palms
• Feeling Uneasiness
• Decreased Testicles size

• Nausea
• Vomiting
• Dry mouth
• Confusion
• weakness
• Bone pain
• Dizziness
• Slow Speech
• Feeling thirsty

• Hematuria
• Fainting
• Seizures
• Blurred Vision
• Difficult Breathing
• Severe Headache

Materna Depot 3.75 mg Injection injection comes as a Long acting Suspension, administered by the Intramuscular or Subcutaneous route in Fatty tissue of the body, generally given around the Navel by skipping 2 inches on either side of the Navel or at the Upper thigh part where tissues are soft. The recommended dose is 1mg given as Songle daily Subcutaneous injection. But the dosage may vary with the Age, sex and Disease condition. So Materna Depot 3.75 mg Injection is advisable to follow the instructions of your Health Care professional. Store it at Room temperature (25°C), do not freeze and keep it away from direct sun light and Children.

Materna Depot 3.75 mg Injection is an agonist of Gonadotropin-releasing hormone receptor, which leads to suppression of Gonadotrope secretion of Luteinizing Hormone and Follicle stimulating hormone. Initially, it increases the level of Estrogen and Testosterone irrespective of sex. But a continuation of this therapy decreases the level of Testosterone in males and estrogen in females.